ConductOrganoid
Phase 3 Vision

ConductChip

Integrated Developmental Neurotoxicity Testing

From stem cell to safety assessment — in any laboratory. A complete, standardized testing system that puts human-relevant neurotoxicity screening within reach of any research lab.

The Problem

Only ~120 compounds have ever been tested for developmental neurotoxicity under OECD TG 426. Each study costs $1-2M, takes 6+ months, and uses rodents with fundamentally different brain development from humans.

The Solution

A complete testing system that any lab can use. Human-relevant iPSC-derived organoids, standardized culture on a microfluidic chip, automated image analysis, and regulatory-grade reporting — all integrated.

Integrated System

Four components work together to deliver a complete developmental neurotoxicity assessment from a single brightfield image.

Hardware

ConductChip

Microfluidic culture device

Protocol

Standard Protocol

Seed, differentiate, dose, image

Existing Equipment

Any Microscope

Standard inverted brightfield

Software

ConductOrganoid

Automated analysis + report

Chip Design

Microscope-slide format microfluidic device with 4 wells, perfusion channels, dosing ports, and an optical-grade bottom.

ConductChip (25 mm x 75 mm)Well 1Well 2Well 3Well 4MediaWasteOptical-grade bottom for brightfield imagingDrug dosing ports~ 50 mm

System Components

Workflow Comparison

Current: OECD TG 426 (Animal)
  1. 1Procure animals
  2. 2House + breed colony
  3. 3Dose pregnant dams daily
  4. 4Wait for birth + litter culling
  5. 5Behavioral testing battery
  6. 6Sacrifice + perfusion fixation
  7. 7Brain sectioning + staining
  8. 8Histopathology + manual scoring

6-12

months

$1-2M

per compound

500+

animals

ConductChip Workflow
  1. 1Seed iPSCs on ConductChip
  2. 2Follow standard protocol (45 days)
  3. 3Add substance at defined doses
  4. 4Image on any inverted microscope
  5. 5Upload to ConductOrganoid
  6. 6Automated multi-modal assessment
  7. 7Regulatory-grade report generated
  8. 8Results in hours, not months

2-3

months

$5-15K

per compound

0

animals

Adoption Model

Everything you need to run developmental neurotoxicity screening — and nothing you don't.

ComponentWhat You GetPricing
ConductChipDisposable 4-8 well microfluidic devicePer chip
Media KitPre-mixed differentiation + exposure reagentsPer kit
ConductOrganoidAnalysis platform + regulatory reportsAnnual subscription
Protocol + TrainingFull documentation + onboardingIncluded

What Your Lab Needs

Standard inverted brightfield microscope
CO2 incubator (standard cell culture)
Biosafety cabinet (standard cell culture)
Organoid expertise(NOT required)
Fluorescence microscope(NOT required)
Custom analysis software(NOT required)
Animal facility(NOT required)

Development Timeline

Phase 2 (2026-27)

NAM Validation

  • Software validated with conventional culture
  • Ethanol + VPA dose-response curves
  • 2 independent labs confirmed
  • NDHCC + VQN engagement initiated
  • Performance standards defined
Phase 3 (2027-28)

ConductChip Integration

  • ConductChip prototype fabricated
  • Head-to-head validation vs conventional culture
  • Multi-substance, multi-lab study
  • VQN prototype delivered to NDHCC
  • OECD alignment initiated

Why ConductScience

ConductScience is an established scientific equipment manufacturer with global distribution serving thousands of research laboratories. We don't just build software — we build and ship scientific instruments.

10+

Years manufacturing scientific equipment

1000+

Active research lab customers worldwide

Global

Distribution and logistics infrastructure

Full Stack

Hardware + software + data integration

Interested in Early Access?

ConductChip is in active development for Phase 3. Contact us to discuss partnership opportunities, early access, or collaboration.